{"id":141354,"date":"2026-10-21T15:56:00","date_gmt":"2026-10-21T12:56:00","guid":{"rendered":"https:\/\/www.clinica-sante.com\/ro\/analize\/panel-genetic-somatic-colorectal-19-gene\/"},"modified":"2026-10-21T15:56:00","modified_gmt":"2026-10-21T12:56:00","slug":"panel-genetic-somatic-colorectal-19-gene","status":"publish","type":"product","link":"https:\/\/www.clinica-sante.com\/ro\/analize-genetica\/panel-genetic-somatic-colorectal-19-gene\/","title":{"rendered":"Panel genetic somatic colorectal &#8211; 19 gene"},"content":{"rendered":"<p><span style=\"color: #252525\">Cancerul colorectal este o afec\u021biune heterogen\u0103 din punct de vedere molecular, iar identificarea modific\u0103rilor genetice ale tumorii poate contribui la caracterizarea mecanismelor biologice implicate \u00een dezvoltarea \u0219i progresia bolii.<\/span><\/p>\n<p><span style=\"color: #252525\">Panelul permite analiza simultan\u0103 a 19 gene cu relevan\u021b\u0103 pentru cancerul colorectal, inclusiv gene implicate \u00een calea MMR, asociat\u0103 cu instabilitatea microsateli\u021bilor (MSI) \u0219i sindromul Lynch, precum \u0219i gene implicate \u00een polipoza colorectal\u0103 \u0219i \u00een principalele c\u0103i moleculare ale carcinogenezei colorectale.<\/span><\/p>\n<p><span style=\"color: #262626\"><strong>Gene analizate<\/strong><\/span><\/p>\n<p><span style=\"color: #262626\">19 gene asociate cancerului colorectal \u0219i sindroamelor ereditare:<\/span><\/p>\n<p><span style=\"color: #262626\"><strong>MLH1, MSH2, MSH6, PMS2, APC, AXIN2, CDH1, CHEK2, EPCAM, MSH3, MUTYH, POLD1, POLE, PTEN, SMAD4, TP53, KRAS, NRAS, BRAF.<\/strong><\/span> <\/p>\n<p><span style=\"color: #262626\">Genele sunt implicate \u00een principal \u00een mecanisme asociate cu:<\/span><\/p>\n<ul>\n<li><span style=\"color: #262626\">repararea ADN-ului \u0219i calea mismatch repair (MMR) <\/span><\/li>\n<li><span style=\"color: #262626\">instabilitatea genomic\u0103<\/span><\/li>\n<li><span style=\"color: #262626\">predispozi\u021bia ereditar\u0103 la cancer colorectal<\/span><\/li>\n<li><span style=\"color: #262626\">polipoza colorectal\u0103<\/span><\/li>\n<li><span style=\"color: #262626\">c\u0103ile de semnalizare implicate \u00een proliferarea tumoral\u0103<\/span><\/li>\n<li><span style=\"color: #262626\">oncogenez\u0103 \u0219i progresie tumoral\u0103<\/span><\/li>\n<li><span style=\"color: #262626\">r\u0103spunsul \u0219i rezisten\u021ba la terapii oncologice<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\">Analiza poate contribui la:<\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">identificarea alter\u0103rilor genetice tumorale relevante<\/span><\/li>\n<li><span style=\"color: #252525\">caracterizarea molecular\u0103 a cancerului colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">evaluarea alter\u0103rilor genelor MMR<\/span><\/li>\n<li> <span style=\"color: #252525\">identificarea unor modific\u0103ri asociate cu sindromul Lynch<\/span><\/li>\n<li><span style=\"color: #252525\">evaluarea genelor asociate polipozei colorectale<\/span><\/li>\n<li><span style=\"color: #252525\">identificarea unor muta\u021bii cu poten\u021bial\u0103 relevan\u021b\u0103 terapeutic\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">sus\u021binerea managementului oncologic personalizat<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Afec\u021biuni sau indica\u021bii clinice<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">adenocarcinom colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">cancer de colon<\/span><\/li>\n<li><span style=\"color: #252525\">cancer de rect<\/span><\/li>\n<li><span style=\"color: #252525\">cancer colorectal local avansat<\/span><\/li>\n<li><span style=\"color: #252525\">cancer colorectal metastatic<\/span><\/li>\n<li><span style=\"color: #252525\">recidiv\u0103 tumoral\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">progresie tumoral\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">cazuri cu suspiciune de instabilitate microsatelitar\u0103 (MSI) <\/span><\/li>\n<li><span style=\"color: #252525\">suspiciune de sindrom Lynch <\/span><\/li>\n<li><span style=\"color: #252525\">cazuri cu suspiciune de sindroame de polipoz\u0103 colorectal\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">suspiciune de polipoz\u0103 adenomatoas\u0103 familial\u0103 (FAP)<\/span> <\/li>\n<li><span style=\"color: #252525\">suspiciune de cancer asociat muta\u021biilor MUTYH <\/span><\/li>\n<li><span style=\"color: #252525\">cazuri \u00een care este necesar\u0103 caracterizarea molecular\u0103 a tumorii<\/span><\/li>\n<li><span style=\"color: #252525\">evaluarea profilului molecular \u00een vederea managementului terapeutic<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Cui se adreseaz\u0103<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">pacien\u021bilor diagnostica\u021bi cu cancer colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">pacien\u021bilor cu boal\u0103 colorectal\u0103 metastatic\u0103 sau recurent\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">cazurilor cu suspiciune de sindrom Lynch<\/span><\/li>\n<li><span style=\"color: #252525\">cazurilor cu suspiciune de polipoz\u0103 colorectal\u0103 ereditar\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">pacien\u021bilor cu un istoric personal sau familial sugestiv pentru cancer colorectal ereditar<\/span><\/li>\n<li><span style=\"color: #252525\">cazurilor \u00een care se dore\u0219te caracterizarea molecular\u0103 a tumorii<\/span><\/li>\n<li><span style=\"color: #252525\">pacien\u021bilor pentru care identificarea unor alter\u0103ri moleculare poate contribui la alegerea managementului terapeutic<\/span><\/li>\n<li><span style=\"color: #252525\">medicilor oncologi \u0219i echipelor multidisciplinare \u2013 tumor board <\/span><\/li>\n<li><span style=\"color: #252525\">anatomopatologilor \u0219i biologilor moleculari<\/span><\/li>\n<li><span style=\"color: #252525\">serviciilor de genetic\u0103 medical\u0103, \u00een cazul suspiciunii unei predispozi\u021bii ereditare<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Metodologie de testare<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\"><strong>secven\u021biere NGS (Next Generation Sequencing)<\/strong><\/span> <\/li>\n<li><span style=\"color: #252525\">analiz\u0103 molecular\u0103 a ADN-ului tumoral<\/span><\/li>\n<li><span style=\"color: #252525\">analiz\u0103 din material tumoral FFPE (formalin-fixed, paraffin-embedded)<\/span><\/li>\n<li><span style=\"color: #252525\">detectarea variantelor SNV (single nucleotide variants) <\/span><\/li>\n<li><span style=\"color: #252525\">detectarea variantelor INDEL \u2013 inser\u021bii \u0219i dele\u021bii<\/span><\/li>\n<li><span style=\"color: #252525\">detectarea CNV (copy number variations) <\/span><\/li>\n<li><span style=\"color: #252525\">analiz\u0103 bioinformatic\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">interpretarea variantelor genetice \u00een context clinic<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Termen de eliberare a rezultatului: 45 de zile lucr\u0103toare<\/strong><\/span> <\/p>\n<p><span style=\"color: #252525\"><strong>Beneficii \u0219i importan\u021b\u0103 clinic\u0103<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">permite profilarea genetic\u0103 a tumorii colorectale<\/span><\/li>\n<li><span style=\"color: #252525\">identific\u0103 variante genetice relevante pentru caracterizarea molecular\u0103 a tumorii<\/span><\/li>\n<li><span style=\"color: #252525\">evalueaz\u0103 gene implicate \u00een sistemul de reparare a ADN-ului<\/span><\/li>\n<li><span style=\"color: #252525\">contribuie la evaluarea alter\u0103rilor asociate c\u0103ii MMR <\/span><\/li>\n<li><span style=\"color: #252525\">poate sus\u021bine evaluarea molecular\u0103 a sindromului Lynch<\/span><\/li>\n<li><span style=\"color: #252525\">contribuie la evaluarea unor forme ereditare de cancer colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">permite investigarea simultan\u0103 a 19 gene relevante<\/span><\/li>\n<li><span style=\"color: #252525\">poate contribui la identificarea unor alter\u0103ri cu relevan\u021b\u0103 terapeutic\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">sprijin\u0103 medicina personalizat\u0103 \u00een oncologie<\/span><\/li>\n<li><span style=\"color: #252525\">poate contribui la evaluarea riscului familial atunci c\u00e2nd rezultatele \u0219i contextul clinic sugereaz\u0103 o predispozi\u021bie ereditar\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">poate ghida investiga\u021biile genetice ulterioare \u0219i evaluarea membrilor familiei, atunci c\u00e2nd este indicat<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Particularit\u0103\u021bi \u0219i limit\u0103ri<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">analiza din \u021besut tumoral este destinat\u0103 \u00een principal <\/span><span style=\"color: #252525\"><strong>caracteriz\u0103rii somatice a tumorii<\/strong><\/span> <\/li>\n<li><span style=\"color: #252525\">rezultatul trebuie interpretat \u00een corela\u021bie cu diagnosticul histopatologic \u0219i datele clinice<\/span><\/li>\n<li><span style=\"color: #252525\">calitatea rezultatului depinde de calitatea materialului FFPE \u0219i de reprezentativitatea probei tumorale<\/span><\/li>\n<li><span style=\"color: #252525\">procentul de celule tumorale din prob\u0103 poate influen\u021ba capacitatea de detec\u021bie a variantelor<\/span><\/li>\n<li><span style=\"color: #252525\">identificarea unei variante \u00een tumoare nu stabile\u0219te automat caracterul ereditar al acesteia<\/span><\/li>\n<li><span style=\"color: #252525\">\u00een cazul unei suspiciuni de predispozi\u021bie ereditar\u0103, poate fi necesar\u0103 confirmarea prin testare germinal\u0103, de regul\u0103 din s\u00e2nge<\/span><\/li>\n<li><span style=\"color: #252525\">rezultatele privind genele MMR trebuie corelate, dup\u0103 caz, cu imunohistochimia proteinelor MMR \u0219i\/sau cu testarea MSI <\/span><\/li>\n<li><span style=\"color: #252525\">variantele genetice trebuie interpretate \u00een context clinic \u0219i familial<\/span><\/li>\n<li><span style=\"color: #252525\">pot fi identificate variante cu semnifica\u021bie clinic\u0103 incert\u0103 (VUS)<\/span><\/li>\n<li><span style=\"color: #252525\">testul genetic nu \u00eenlocuie\u0219te examenul histopatologic<\/span><\/li>\n<li><span style=\"color: #252525\">rezultatul nu trebuie interpretat izolat pentru stabilirea conduitei terapeutice<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Tip de prob\u0103<\/strong><\/span><\/p>\n<p><span style=\"color: #252525\"><strong>Pentru analiza tumoral\u0103:<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\"><strong>\u021besut tumoral inclus \u00een parafin\u0103<\/strong><\/span><span style=\"color: #252525\"> (<\/span><span style=\"color: #252525\"><strong>FFPE<\/strong><\/span><span style=\"color: #252525\">)<\/span><\/li>\n<li><span style=\"color: #252525\">bloc tumoral<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Recoltare \u0219i condi\u021bii<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">proba tumoral\u0103 trebuie s\u0103 provin\u0103 din biopsie sau pies\u0103 operatorie<\/span><\/li>\n<li><span style=\"color: #252525\">este necesar\u0103 evaluarea histopatologic\u0103 a materialului<\/span><\/li>\n<li><span style=\"color: #252525\">se recomand\u0103 selectarea unei zone reprezentative de \u021besut tumoral<\/span><\/li>\n<li><span style=\"color: #252525\">materialul trebuie s\u0103 fie corespunz\u0103tor pentru extrac\u021bia ADN-ului \u0219i analiza NGS<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Denumiri alternative<\/strong><\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">Panel genetic somatic cancer colorectal \u2013 19 gene<\/span><\/li>\n<li><span style=\"color: #252525\">Panel genetic colorectal 19 gene<\/span><\/li>\n<li><span style=\"color: #252525\">Test NGS tumoral cancer colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">Profil molecular tumoral colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">Panel oncogenetic somatic colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">Test genetic cancer colorectal \u2013 muta\u021bii somatice<\/span><\/li>\n<li><span style=\"color: #252525\">Panel colorectal MMR + cancer-associated genes <\/span><\/li>\n<li><span style=\"color: #252525\">Colorectal Cancer NGS Panel<\/span><\/li>\n<li><span style=\"color: #252525\">Colorectal Cancer Test<\/span><\/li>\n<\/ul>\n<p><span style=\"color: #252525\"><strong>Analize asociate recomandate<\/strong><\/span><\/p>\n<p><span style=\"color: #252525\">\u00cen func\u021bie de indica\u021bia clinic\u0103, rezultatul panelului poate fi corelat cu:<\/span><\/p>\n<ul>\n<li><span style=\"color: #252525\">examen histopatologic<\/span><\/li>\n<li><span style=\"color: #252525\">imunohistochimie MMR: MLH1, MSH2, MSH6, PMS2 <\/span><\/li>\n<li><span style=\"color: #252525\">testarea instabilit\u0103\u021bii microsateli\u021bilor (MSI) <\/span><\/li>\n<li><span style=\"color: #252525\">analiza BRAF, \u00een contextul evalu\u0103rii statusului MMR\/Lynch<\/span><\/li>\n<li><span style=\"color: #252525\">evaluarea clinic\u0103 \u0219i familial\u0103 pentru sindromul Lynch<\/span><\/li>\n<li><span style=\"color: #252525\">testare genetic\u0103 germinal\u0103 pentru predispozi\u021bia ereditar\u0103, atunci c\u00e2nd este indicat\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">investiga\u021bii pentru sindroame de polipoz\u0103 ereditar\u0103<\/span><\/li>\n<li><span style=\"color: #252525\">evaluarea KRAS\/NRAS\/BRAF \u00een contextul managementului terapeutic al cancerului colorectal<\/span><\/li>\n<li><span style=\"color: #252525\">imagistic\u0103 oncologic\u0103: CT, RMN, PET-CT, dup\u0103 indica\u021bie<\/span><\/li>\n<li><span style=\"color: #252525\">consult oncologic<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Panelul genetic somatic pentru cancerul colorectal analizeaz\u0103 un set de <strong>19 gene implicate \u00een dezvoltarea, progresia \u0219i caracterizarea molecular\u0103 a cancerului colorectal<\/strong>, utiliz\u00e2nd tehnologia NGS (Next Generation Sequencing).<\/p>\n<p>Testul permite identificarea unor <strong>variante genetice somatice relevante clinic<\/strong>\u00a0la nivelul tumorii, inclusiv variante SNV, INDEL \u0219i CNV, contribuind la caracterizarea molecular\u0103 a tumorii, evaluarea unor mecanisme asociate carcinogenezei \u0219i orientarea managementului oncologic personalizat.<\/p>\n<p>Panelul include gene implicate \u00een <strong>repararea ADN-ului prin mecanismul mismatch repair (MMR)<\/strong>, precum <strong>MLH1, MSH2, MSH6 \u0219i PMS2<\/strong>, precum \u0219i gene cu rol important \u00een cancerul colorectal, cum ar fi <strong>APC, KRAS, NRAS, BRAF \u0219i MUTYH<\/strong>.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"product_brand":[],"product_cat":[1209,5015,5016,3165,2876],"product_tag":[],"class_list":["post-141354","product","type-product","status-publish","product_cat-analize","product_cat-genetica","product_cat-genetica-moleculara","product_cat-oncogenetica","product_cat-serviciu-laborator","first","instock","sale","virtual","purchasable","product-type-simple"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 5.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Panelul genetic somatic pentru cancerul colorectal analizeaz\u0103 un set de 19 gene implicate \u00een dezvoltarea, progresia \u0219i caracterizarea molecular\u0103 a cancerului colorectal, utiliz\u00e2nd tehnologia NGS (Next Generation Sequencing). Testul permite identificarea unor variante genetice somatice relevante clinic la nivelul tumorii, inclusiv variante SNV, INDEL \u0219i CNV, contribuind la caracterizarea molecular\u0103 a tumorii, evaluarea unor mecanisme asociate carcinogenezei \u0219i orientarea managementului oncologic personalizat. Panelul include gene implicate \u00een repararea ADN-ului prin mecanismul mismatch repair (MMR), precum MLH1, MSH2, MSH6 \u0219i PMS2, precum \u0219i gene cu rol important \u00een cancerul colorectal, cum ar fi APC, KRAS, NRAS, BRAF \u0219i MUTYH.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.clinica-sante.com\/ro\/analize-genetica\/panel-genetic-somatic-colorectal-19-gene\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO Pro (AIOSEO) 5.0.1\" \/>\n\t\t<meta property=\"og:locale\" content=\"ro_RO\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Clinica Sante - Laborator de Analize Medicale - Clinica Sante - Laborator de Analize Medicale\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"Panel genetic somatic colorectal \u2013 19 gene - Clinica Sante - Laborator de Analize Medicale\" \/>\n\t\t<meta property=\"og:description\" content=\"Panelul genetic somatic pentru cancerul colorectal analizeaz\u0103 un set de 19 gene implicate \u00een dezvoltarea, progresia \u0219i caracterizarea molecular\u0103 a cancerului colorectal, utiliz\u00e2nd tehnologia NGS (Next Generation Sequencing). Testul permite identificarea unor variante genetice somatice relevante clinic la nivelul tumorii, inclusiv variante SNV, INDEL \u0219i CNV, contribuind la caracterizarea molecular\u0103 a tumorii, evaluarea unor mecanisme asociate carcinogenezei \u0219i orientarea managementului oncologic personalizat. Panelul include gene implicate \u00een repararea ADN-ului prin mecanismul mismatch repair (MMR), precum MLH1, MSH2, MSH6 \u0219i PMS2, precum \u0219i gene cu rol important \u00een cancerul colorectal, cum ar fi APC, KRAS, NRAS, BRAF \u0219i MUTYH.\" \/>\n\t\t<meta property=\"og:url\" content=\"https:\/\/www.clinica-sante.com\/ro\/analize-genetica\/panel-genetic-somatic-colorectal-19-gene\/\" \/>\n\t\t<meta property=\"article:published_time\" content=\"2026-10-21T12:56:00+00:00\" \/>\n\t\t<meta property=\"article:modified_time\" content=\"2026-10-21T12:56:00+00:00\" \/>\n\t\t<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n\t\t<meta name=\"twitter:title\" content=\"Panel genetic somatic colorectal \u2013 19 gene - Clinica Sante - Laborator de Analize Medicale\" \/>\n\t\t<meta name=\"twitter:description\" content=\"Panelul genetic somatic pentru cancerul colorectal analizeaz\u0103 un set de 19 gene implicate \u00een dezvoltarea, progresia \u0219i caracterizarea molecular\u0103 a cancerului colorectal, utiliz\u00e2nd tehnologia NGS (Next Generation Sequencing). Testul permite identificarea unor variante genetice somatice relevante clinic la nivelul tumorii, inclusiv variante SNV, INDEL \u0219i CNV, contribuind la caracterizarea molecular\u0103 a tumorii, evaluarea unor mecanisme asociate carcinogenezei \u0219i orientarea managementului oncologic personalizat. 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Testul permite identificarea unor variante genetice somatice relevante clinic la nivelul tumorii, inclusiv variante SNV, INDEL \u0219i CNV, contribuind la caracterizarea molecular\u0103 a tumorii, evaluarea unor mecanisme asociate carcinogenezei \u0219i orientarea managementului oncologic personalizat. Panelul include gene implicate \u00een repararea ADN-ului prin mecanismul mismatch repair (MMR), precum MLH1, MSH2, MSH6 \u0219i PMS2, precum \u0219i gene cu rol important \u00een cancerul colorectal, cum ar fi APC, KRAS, NRAS, BRAF \u0219i MUTYH.","og:url":"https:\/\/www.clinica-sante.com\/ro\/analize-genetica\/panel-genetic-somatic-colorectal-19-gene\/","article:published_time":"2026-10-21T12:56:00+00:00","article:modified_time":"2026-10-21T12:56:00+00:00","twitter:card":"summary_large_image","twitter:title":"Panel genetic somatic colorectal \u2013 19 gene - Clinica Sante - Laborator de Analize Medicale","twitter:description":"Panelul genetic somatic pentru cancerul colorectal analizeaz\u0103 un set de 19 gene implicate \u00een dezvoltarea, progresia \u0219i caracterizarea molecular\u0103 a cancerului colorectal, utiliz\u00e2nd tehnologia NGS (Next Generation Sequencing). Testul permite identificarea unor variante genetice somatice relevante clinic la nivelul tumorii, inclusiv variante SNV, INDEL \u0219i CNV, contribuind la caracterizarea molecular\u0103 a tumorii, evaluarea unor mecanisme asociate carcinogenezei \u0219i orientarea managementului oncologic personalizat. Panelul include gene implicate \u00een repararea ADN-ului prin mecanismul mismatch repair (MMR), precum MLH1, MSH2, MSH6 \u0219i PMS2, precum \u0219i gene cu rol important \u00een cancerul colorectal, cum ar fi APC, KRAS, NRAS, BRAF \u0219i MUTYH."},"aioseo_meta_data":{"post_id":"141354","title":null,"description":null,"keywords":null,"keyphrases":{"focus":[],"additional":[]},"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":null,"og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":false,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":null,"robots_max_videopreview":null,"robots_max_imagepreview":"large","priority":null,"frequency":null,"local_seo":null,"seo_analyzer_scan_date":null,"breadcrumb_settings":null,"limit_modified_date":false,"open_ai":null,"ai":null,"created":"2026-10-21 12:56:00","updated":"2026-10-21 16:39:19","focus_keyword":null,"additional_keywords":null,"truseo_locale":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/www.clinica-sante.com\/ro\" title=\"Prima pagin\u0103\">Prima pagin\u0103<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/www.clinica-sante.com\/ro\/analize-medicale\/\" title=\"Analize Medicale\">Analize Medicale<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/www.clinica-sante.com\/ro\/analize\/\" title=\"Analize\">Analize<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/www.clinica-sante.com\/ro\/analize-serviciu-laborator\/\" title=\"Serviciu laborator\">Serviciu laborator<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/www.clinica-sante.com\/ro\/analize-genetica\/\" title=\"Genetic\u0103\">Genetic\u0103<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\t<a href=\"https:\/\/www.clinica-sante.com\/ro\/analize-genetica-moleculara\/\" title=\"Genetic\u0103 molecular\u0103\">Genetic\u0103 molecular\u0103<\/a>\n<\/span><span class=\"aioseo-breadcrumb-separator\">&raquo;<\/span><span class=\"aioseo-breadcrumb\">\n\tPanel genetic somatic colorectal \u2013 19 gene\n<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Prima pagin\u0103","link":"https:\/\/www.clinica-sante.com\/ro"},{"label":"Analize Medicale","link":"https:\/\/www.clinica-sante.com\/ro\/analize-medicale\/"},{"label":"Analize","link":"https:\/\/www.clinica-sante.com\/ro\/analize\/"},{"label":"Serviciu laborator","link":"https:\/\/www.clinica-sante.com\/ro\/analize-serviciu-laborator\/"},{"label":"Genetic\u0103","link":"https:\/\/www.clinica-sante.com\/ro\/analize-genetica\/"},{"label":"Genetic\u0103 molecular\u0103","link":"https:\/\/www.clinica-sante.com\/ro\/analize-genetica-moleculara\/"},{"label":"Panel genetic somatic colorectal &#8211; 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