{"id":128744,"date":"2026-09-14T12:38:04","date_gmt":"2026-09-14T09:38:04","guid":{"rendered":"https:\/\/www.clinica-sante.com\/ro\/analize\/ige-specific-la-venin-de-albina-rapi-m10-icarapin-i217\/"},"modified":"2026-10-21T19:42:30","modified_gmt":"2026-10-21T16:42:30","slug":"ige-specific-la-venin-de-albina-rapi-m10-icarapin-i217","status":"publish","type":"product","link":"https:\/\/www.clinica-sante.com\/ro\/analize-alergologie\/ige-specific-la-venin-de-albina-rapi-m10-icarapin-i217\/","title":{"rendered":"IgE specific la venin de albina rApi m10 &#8211; Icarapin (i217)"},"content":{"rendered":"<h2><span style=\"color: #e67e23\">1. Descriere general\u0103<\/span><\/h2>\n<p>IgE specific la venin de albin\u0103 rApi m 10 \u2013 Icarapin (i217) este o analiz\u0103 de s\u00e2nge care evalueaz\u0103 prezen\u021ba anticorpilor IgE specifici fa\u021b\u0103 de rApi m 10, o component\u0103 molecular\u0103 din veninul de albin\u0103.<\/p>\n<p>IgE sunt anticorpi produ\u0219i de sistemul imunitar. \u00cen alergiile IgE-mediate, organismul percepe \u00een mod gre\u0219it anumite substan\u021be ca fiind periculoase. Aceste substan\u021be se numesc alergeni. \u00cen cazul alergiei la venin de albin\u0103, reac\u021bia poate ap\u0103rea dup\u0103 \u00een\u021bep\u0103tur\u0103, atunci c\u00e2nd sistemul imunitar recunoa\u0219te anumite proteine din venin \u0219i declan\u0219eaz\u0103 un r\u0103spuns alergic.<\/p>\n<p>Api m 10, cunoscut \u0219i sub denumirea de icarapin, este una dintre componentele alergene importante ale veninului de albin\u0103. Testarea formei recombinante, rApi m 10, face parte din diagnosticul molecular al alergiilor \u0219i poate contribui la demonstrarea unei sensibiliz\u0103ri autentice la veninul de albin\u0103.<\/p>\n<p>Analiza poate fi util\u0103 mai ales la persoanele care au avut reac\u021bii alercice dup\u0103 \u00een\u021bep\u0103tura de albin\u0103, de la manifest\u0103ri cutanate extinse p\u00e2n\u0103 la reac\u021bii alergice care pot afecta \u00eentregul organism. \u00a0<\/p>\n<p>Simptomele pot include:<\/p>\n<ul>\n<li>urticarie generalizat\u0103;<\/li>\n<li>m\u00e2nc\u0103rimi extinse;<\/li>\n<li>\u00eenro\u0219irea pielii;<\/li>\n<li>umflarea buzelor, pleoapelor, fe\u021bei sau limbii;<\/li>\n<li>senza\u021bie de nod \u00een g\u00e2t;<\/li>\n<li>dificult\u0103\u021bi de respira\u021bie;<\/li>\n<li>respira\u021bie \u0219uier\u0103toare;<\/li>\n<li>ame\u021beal\u0103 sau stare de le\u0219in;<\/li>\n<li>grea\u021b\u0103, v\u0103rs\u0103turi, dureri abdominale sau diaree;<\/li>\n<li>sc\u0103derea tensiunii arteriale;<\/li>\n<li>reac\u021bie anafilactic\u0103.<\/li>\n<\/ul>\n<p>Testarea rApi m 10 poate fi util\u0103 la pacien\u021bii cu suspiciune de alergie la venin de albin\u0103, mai ales atunci c\u00e2nd rezultatele la alte componente ale veninului nu explic\u0103 suficient tabloul clinic. De asemenea, poate contribui la evaluarea profilului de sensibilizare la pacien\u021bii care au avut reac\u021bii dup\u0103 \u00een\u021bep\u0103turi de albin\u0103, viespe sau alte insecte cu venin, mai ales atunci c\u00e2nd rezultatele sunt pozitive la mai multe tipuri de venin.<\/p>\n<p>Un rezultat pozitiv indic\u0103 prezen\u021ba anticorpilor IgE specifici fa\u021b\u0103 de rApi m 10, dar nu confirm\u0103 singur existen\u021ba unei alergii clinice. Unele persoane pot avea sensibilizare detectabil\u0103 f\u0103r\u0103 s\u0103 prezinte reac\u021bii relevante la \u00een\u021bep\u0103turi. De aceea, rezultatul trebuie interpretat \u00eempreun\u0103 cu istoricul medical, tipul reac\u021biei ap\u0103rute dup\u0103 \u00een\u021bep\u0103tur\u0103, insecta suspectat\u0103, severitatea manifest\u0103rilor \u0219i recomand\u0103rile medicului alergolog.<\/p>\n<p>Analiza nu stabile\u0219te singur\u0103 riscul de anafilaxie \u0219i nu \u00eenlocuie\u0219te consultul alergologic. Rezultatul poate \u00eens\u0103 ajuta medicul s\u0103 confirme sensibilizarea la veninul de albin\u0103 \u0219i s\u0103 stabileasc\u0103 recomand\u0103ri privind evitarea expunerii, conduita \u00een caz de \u00een\u021bep\u0103tur\u0103, necesitatea unui plan de urgen\u021b\u0103 sau evaluarea pentru imunoterapie cu venin, atunci c\u00e2nd este cazul.<\/p>\n<h2><span style=\"color: #e67e23\">2. Indica\u021bii testare<\/span><\/h2>\n<ul>\n<li>Evaluarea pacien\u021bilor care au prezentat reac\u021bii alergice generalizate dup\u0103 \u00een\u021bep\u0103tura de albin\u0103, precum urticarie extins\u0103 sau angioedem;<\/li>\n<li>Evaluarea reac\u021biilor severe, cu dificult\u0103\u021bi de respira\u021bie, respira\u021bie \u0219uier\u0103toare, ame\u021beal\u0103, stare de le\u0219in, sc\u0103derea tensiunii arteriale sau suspiciune de anafilaxie;<\/li>\n<li>Clarificarea sensibiliz\u0103rii la venin de albin\u0103 la pacien\u021bii cu istoric sugestiv, dar cu rezultate alergologice dificil de interpretat;<\/li>\n<li>Completarea evalu\u0103rii alergologice la pacien\u021bii pentru care se ia \u00een considerare imunoterapia cu venin, atunci c\u00e2nd caracterizarea molecular\u0103 a sensibiliz\u0103rii este relevant\u0103;<\/li>\n<li>Evaluarea pacien\u021bilor cu rezultate pozitive la mai multe veninuri de himenoptere, atunci c\u00e2nd este necesar\u0103 diferen\u021bierea sensibiliz\u0103rii la venin de albin\u0103 de sensibilizarea la alte insecte;<\/li>\n<li>Sprijinirea deciziei medicale privind m\u0103surile de evitare, planul de urgen\u021b\u0103 sau evaluarea pentru imunoterapie cu venin, conform recomand\u0103rii medicului alergolog.<\/li>\n<\/ul>\n<h2>3. Preg\u0103tire pacient \u0219i mod de recoltare<\/h2>\n<ul>\n<li>Nu este necesar\u0103, \u00een general, o preg\u0103tire alimentar\u0103 special\u0103. Dac\u0103 analiza este recoltat\u0103 \u00eempreun\u0103 cu alte teste, se respect\u0103 condi\u021biile de preg\u0103tire indicate pentru acestea \u0219i instruc\u021biunile laboratorului.<\/li>\n<li>Tratamentul prescris se continu\u0103, dac\u0103 medicul nu indic\u0103 altfel.<\/li>\n<li>Este important ca medicul s\u0103 fie informat despre reac\u021bia ap\u0103rut\u0103 dup\u0103 \u00een\u021bep\u0103tur\u0103, momentul apari\u021biei simptomelor, severitatea manifest\u0103rilor, insecta suspectat\u0103, tratamentul administrat, antecedentele de anafilaxie, astm, alte alergii sau tratamente alergologice anterioare.<\/li>\n<li>Dac\u0103 analiza este efectuat\u0103 prea cur\u00e2nd dup\u0103 reac\u021bia alergic\u0103, rezultatul poate fi negativ. \u00cen aceast\u0103 situa\u021bie, medicul alergolog poate recomanda repetarea test\u0103rii dup\u0103 c\u00e2teva s\u0103pt\u0103m\u00e2ni.<\/li>\n<li>Rezultatul trebuie interpretat \u00een context clinic. Un rezultat pozitiv indic\u0103 sensibilizare la rApi m 10, dar nu confirm\u0103 singur c\u0103 veninul de albin\u0103 este cauza reac\u021biei.<\/li>\n<\/ul>\n<h2><span style=\"color: #e67e23\">4. Tipul probei recoltate<\/span><\/h2>\n<ul>\n<li>S\u00e2nge venos.<\/li>\n<\/ul>\n<h2><span style=\"color: #e67e23\">5. Valori de referin\u021b\u0103<\/span><\/h2>\n<p>Valorile pot varia \u00een func\u021bie de laborator \u0219i de metoda utilizat\u0103.<\/p>\n<ul>\n<li>Rezultat negativ: anticorpi IgE specifici nedetectabili sau sub limita de referin\u021b\u0103 a laboratorului.<\/li>\n<li>Rezultat pozitiv: anticorpi IgE specifici detectabili fa\u021b\u0103 de rApi m 10 \u2013 icarapin din veninul de albin\u0103.<\/li>\n<\/ul>\n<p>\u00cen multe laboratoare, rezultatul este exprimat cantitativ, \u00een kUA\/L, \u0219i\/sau \u00eencadrat pe clase de reactivitate. Interpretarea trebuie f\u0103cut\u0103 \u00een func\u021bie de intervalele comunicate pe buletinul de analiz\u0103.<\/p>\n<h2><span style=\"color: #e67e23\">6. Interpretare rezultate<\/span><\/h2>\n<h3>Rezultat negativ<\/h3>\n<ul>\n<li>Nu eviden\u021biaz\u0103 sensibilizare IgE detectabil\u0103 fa\u021b\u0103 de rApi m 10 la momentul test\u0103rii<\/li>\n<li>Face mai pu\u021bin probabil\u0103 sensibilizarea specific\u0103 fa\u021b\u0103 de aceast\u0103 component\u0103 a veninului de albin\u0103<\/li>\n<li>Nu exclude complet alergia la venin de albin\u0103, deoarece unii pacien\u021bi pot fi sensibiliza\u021bi la alte componente ale veninului, precum Api m 1 sau alte molecule alergene<\/li>\n<li>Dac\u0103 istoricul de reac\u021bie dup\u0103 \u00een\u021bep\u0103tur\u0103 este sugestiv, medicul poate recomanda testarea IgE fa\u021b\u0103 de extractul total de venin de albin\u0103, alte componente moleculare ale veninului sau teste alergologice suplimentare.<\/li>\n<\/ul>\n<h3>Rezultat pozitiv\/ anticorpi IgE specifici detecta\u021bi peste pragul de pozitivitate al metodei<\/h3>\n<ul>\n<li>Indic\u0103 prezen\u021ba anticorpilor IgE specifici fa\u021b\u0103 de rApi m 10;<\/li>\n<li>Sus\u021bine sensibilizarea fa\u021b\u0103 de veninul de albin\u0103, mai ales dac\u0103 pacientul a avut simptome dup\u0103 \u00een\u021bep\u0103tur\u0103 de albin\u0103;<\/li>\n<li>Poate fi util la pacien\u021bii cu suspiciune de alergie la venin de albin\u0103 \u0219i rezultate negative sau neconcludente la alte componente moleculare;<\/li>\n<li>Poate contribui la stabilirea profilului alergologic molecular \u0219i la evaluarea pacientului pentru imunoterapie cu venin, atunci c\u00e2nd exist\u0103 indica\u021bie clinic\u0103;<\/li>\n<li>Poate avea relevan\u021b\u0103 suplimentar\u0103 la pacien\u021bii cu sensibilizare predominant\u0103 la Api m 10, deoarece aceast\u0103 component\u0103 poate fi subreprezentat\u0103 \u00een unele preparate utilizate pentru imunoterapia cu venin de albin\u0103. Semnifica\u021bia acestui profil se stabile\u0219te de c\u0103tre medicul alergolog.<\/li>\n<\/ul>\n<p><strong>Important:<\/strong> valoarea IgE specific\u0103 nu se coreleaz\u0103 \u00eentotdeauna direct cu severitatea reac\u021biei. Un rezultat pozitiv trebuie interpretat \u00eempreun\u0103 cu istoricul pacientului, tipul reac\u021biei dup\u0103 \u00een\u021bep\u0103tur\u0103 \u0219i evaluarea medicului alergolog.<\/p>\n<h2><span style=\"color: #e67e23\">7. Factori care pot influen\u021ba interpretarea rezultatului<\/span><\/h2>\n<ul>\n<li>Momentul test\u0103rii dup\u0103 \u00een\u021bep\u0103tur\u0103 \u2013 dac\u0103 analiza este efectuat\u0103 prea cur\u00e2nd dup\u0103 reac\u021bia alergic\u0103, rezultatul poate fi negativ. \u00cen aceast\u0103 situa\u021bie, medicul poate recomanda repetarea test\u0103rii dup\u0103 c\u00e2teva s\u0103pt\u0103m\u00e2ni;<\/li>\n<li>Sensibilizarea la mai multe veninuri de insecte, care poate \u00eengreuna identificarea insectei responsabile;<\/li>\n<li>Sensibilizarea la alte componente ale veninului de albin\u0103 \u2013 un rezultat negativ pentru rApi m 10 nu exclude sensibilizarea la alte molecule alergene din venin;<\/li>\n<li>Interpretarea rezultatului f\u0103r\u0103 corelare cu istoricul clinic, tipul reac\u021biei, insecta suspectat\u0103 \u0219i evaluarea alergologic\u0103.<\/li>\n<\/ul>\n<h2><span style=\"color: #e67e23\">8. Analize complementare<\/span><\/h2>\n<ul>\n<li><strong>IgE specific la venin de albine (i1)<\/strong> \u2013 util pentru evaluarea sensibiliz\u0103rii fa\u021b\u0103 de extractul total de venin de albin\u0103, mai ales la pacien\u021bii cu reac\u021bii dup\u0103 \u00een\u021bep\u0103tur\u0103, atunci c\u00e2nd se dore\u0219te corelarea rezultatului molecular cu extractul complet<\/li>\n<li><strong>IgE specific la venin de albin\u0103 rApi m 1 \u2013 fosfolipaza A2 (i208)<\/strong> \u2013 util pentru evaluarea sensibiliz\u0103rii fa\u021b\u0103 de Api m 1, una dintre componentele alergene majore ale veninului de albin\u0103<\/li>\n<li><strong>IgE specific la venin de viespe comuna (Vespula) (i3)<\/strong> \u2013 util pentru evaluarea sensibiliz\u0103rii fa\u021b\u0103 de extractul total de venin de viespe comun\u0103, mai ales dac\u0103 insecta responsabil\u0103 pentru reac\u021bie nu este clar identificat\u0103<\/li>\n<li><strong>IgE specific la venin de viespe comuna (antigen recombinant rVes v 1, fosfolipaza A1) (i211)<\/strong> \u2013 util pentru evaluarea molecular\u0103 a sensibiliz\u0103rii la venin de viespe comun\u0103 \u0219i pentru diferen\u021bierea fa\u021b\u0103 de sensibilizarea la venin de albin\u0103<\/li>\n<li><strong>IgE specific la venin de viespe comuna (antigen recombinant rVes v 5, antigen 5) (i209)<\/strong> \u2013 util pentru completarea diagnosticului molecular al alergiei la venin de viespe comun\u0103, \u00een special la pacien\u021bii cu suspiciune clinic\u0103 \u0219i profil alergologic complex<\/li>\n<li><strong>IgE specific la venin de viespe de hartie (Polistes spp.) (i4)<\/strong> \u2013 util pentru evaluarea sensibiliz\u0103rii fa\u021b\u0103 de veninul de viespe de h\u00e2rtie, \u00een cazurile \u00een care istoricul sugereaz\u0103 o posibil\u0103 reac\u021bie la acest tip de insect\u0103<\/li>\n<li><strong>IgE specific la viespe europeana (Vespa crabro) (i75)<\/strong> \u2013 util pentru evaluarea sensibiliz\u0103rii fa\u021b\u0103 de veninul de viespe european\u0103, mai ales la pacien\u021bii cu reac\u021bii dup\u0103 \u00een\u021bep\u0103turi de himenoptere \u0219i insect\u0103 responsabil\u0103 incert\u0103<\/li>\n<li><strong>Triptaza seric\u0103 \u2013 <\/strong>poate fi indicat\u0103 \u00een evaluarea anafilaxiei \u0219i, prin determinarea valorii bazale, pentru identificarea unor factori de risc asocia\u021bi activ\u0103rii sau bolilor mastocitare<\/li>\n<li><strong>IgE seric<\/strong> \u2013 util pentru evaluarea nivelului total al imunoglobulinelor E, f\u0103r\u0103 a identifica \u00eens\u0103 alergenul responsabil<\/li>\n<li><strong>Consult alergologic \u0219i, la indica\u021bia medicului, teste cutanate alergologice sau alte investiga\u021bii specifice<\/strong> \u2013 utile pentru corelarea rezultatelor de laborator cu istoricul reac\u021biei, insecta suspectat\u0103 \u0219i tabloul clinic.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Testul detecteaz\u0103 anticorpii IgE specifici fa\u021b\u0103 de rApi m 10, icarapin, o component\u0103 alergen\u0103 important\u0103 a veninului de albin\u0103. Este util \u00een evaluarea reac\u021biilor alergice ap\u0103rute dup\u0103 \u00een\u021bep\u0103tura de albin\u0103 \u0219i \u00een completarea diagnosticului molecular al alergiei la venin de albin\u0103.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"product_brand":[],"product_cat":[3151,1209,2876],"product_tag":[4720,4717,4716,4734,4721,4730,4719,4725,4732,4731,4713,4726,4729,4722,4697,4733,4723,4718],"class_list":["post-128744","product","type-product","status-publish","product_cat-alergologie","product_cat-analize","product_cat-serviciu-laborator","product_tag-alergie-himenoptere","product_tag-alergie-la-intepatura-de-albina","product_tag-alergie-la-venin-de-albina","product_tag-alergologie","product_tag-anafilaxie","product_tag-api-m-10","product_tag-apis-mellifera","product_tag-diagnostic-molecular-alergii","product_tag-i217","product_tag-icarapin","product_tag-ige-specific-venin-de-albina","product_tag-imunoterapie-cu-venin","product_tag-rapi-m-10","product_tag-reactie-alergica-la-intepatura","product_tag-sensibilizare-ige","product_tag-umflarea-fetei-dupa-intepatura","product_tag-urticarie-generalizata","product_tag-venin-de-albine","first","instock","sale","shipping-taxable","purchasable","product-type-simple"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 5.0.1 - aioseo.com -->\n\t<meta name=\"description\" content=\"Testul detecteaz\u0103 anticorpii IgE specifici fa\u021b\u0103 de rApi m 10, icarapin, o component\u0103 alergen\u0103 important\u0103 a veninului de albin\u0103. Este util \u00een evaluarea reac\u021biilor alergice ap\u0103rute dup\u0103 \u00een\u021bep\u0103tura de albin\u0103 \u0219i \u00een completarea diagnosticului molecular al alergiei la venin de albin\u0103.\" \/>\n\t<meta name=\"robots\" content=\"max-image-preview:large\" \/>\n\t<link rel=\"canonical\" href=\"https:\/\/www.clinica-sante.com\/ro\/analize-alergologie\/ige-specific-la-venin-de-albina-rapi-m10-icarapin-i217\/\" \/>\n\t<meta name=\"generator\" content=\"All in One SEO Pro (AIOSEO) 5.0.1\" \/>\n\t\t<meta property=\"og:locale\" content=\"ro_RO\" \/>\n\t\t<meta property=\"og:site_name\" content=\"Clinica Sante - Laborator de Analize Medicale - Clinica Sante - Laborator de Analize Medicale\" \/>\n\t\t<meta property=\"og:type\" content=\"article\" \/>\n\t\t<meta property=\"og:title\" content=\"IgE specific la venin de albina rApi m10 \u2013 Icarapin (i217) - Clinica Sante - Laborator de Analize Medicale\" \/>\n\t\t<meta property=\"og:description\" content=\"Testul detecteaz\u0103 anticorpii IgE specifici fa\u021b\u0103 de rApi m 10, icarapin, o component\u0103 alergen\u0103 important\u0103 a veninului de albin\u0103. 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