{"id":105463,"date":"2026-06-15T16:29:49","date_gmt":"2026-06-15T13:29:49","guid":{"rendered":"https:\/\/www.clinica-sante.com\/ro\/analize\/profil-qf-pcr-cariotip-lichid-amniotic\/"},"modified":"2026-06-15T16:29:49","modified_gmt":"2026-06-15T13:29:49","slug":"profil-qf-pcr-cariotip-lichid-amniotic","status":"publish","type":"product","link":"https:\/\/www.clinica-sante.com\/ro\/pachete\/profil-qf-pcr-cariotip-lichid-amniotic\/","title":{"rendered":"Profil QF-PCR + cariotip (lichid amniotic)"},"content":{"rendered":"

Profilul QF-PCR \u0219i cariotipul din lichid amniotic reprezint\u0103 o analiz\u0103 genetic\u0103 prenatal\u0103 complex\u0103, realizat\u0103 pe lichid amniotic ob\u021binut prin amniocentez\u0103, cu scopul evalu\u0103rii complete a cromozomilor fetali.<\/p>\n

Componenta QF-PCR (Quantitative Fluorescent PCR)<\/strong> permite detectarea rapid\u0103 a celor mai frecvente aneuploidii fetale (cromozomii 13, 18, 21 \u0219i gonozomii X\/Y), oferind un rezultat rapid, util \u00een deciziile clinice precoce.<\/p>\n

Componenta de cariotip fetal<\/strong>, ob\u021binut\u0103 prin cultur\u0103 celular\u0103 din lichid amniotic<\/strong>, permite analiza complet\u0103 a setului cromozomial, identific\u00e2nd anomalii numerice \u0219i structurale (dele\u021bii mari, duplica\u021bii, transloca\u021bii, inversii).<\/p>\n

Asocierea celor dou\u0103 metode ofer\u0103 un diagnostic prenatal extins, combin\u00e2nd rapiditatea QF-PCR cu rezolu\u021bia structural\u0103 a cariotipului.<\/p>\n

Indica\u021bii de testare<\/h3>\n
    \n
  • Screening prenatal cu risc crescut (test combinat \/ NIPT pozitiv)<\/li>\n
  • V\u00e2rst\u0103 matern\u0103 avansat\u0103<\/li>\n
  • Ecografie fetal\u0103 cu anomalii structurale sau markeri sugestivi<\/li>\n
  • Translucen\u021b\u0103 nucal\u0103 crescut\u0103<\/li>\n
  • Istoric de sarcini cu anomalii cromozomiale<\/li>\n
  • Suspiciune de aneuploidii fetale<\/li>\n
  • Consiliere genetic\u0103 prenatal\u0103<\/li>\n
  • Decizie medical\u0103 dup\u0103 screening prenatal modificat<\/li>\n<\/ul>\n

    Cui se adreseaz\u0103<\/h3>\n
      \n
    • Gravide cu sarcin\u0103 cu risc genetic crescut<\/li>\n
    • Sarcini cu anomalii ecografice fetale<\/li>\n
    • Paciente cu screening prenatal modificat<\/li>\n
    • Cupluri cu antecedente de anomalii cromozomiale<\/li>\n
    • Paciente evaluate \u00een servicii de obstetric\u0103 \u0219i genetic\u0103 medical\u0103<\/li>\n<\/ul>\n

      Metodologie de testare<\/h3>\n
        \n
      • QF-PCR (Quantitative Fluorescent PCR)<\/strong> pentru cromozomii 13, 18, 21, X \u0219i Y<\/li>\n
      • Analiza markerilor STR specifici pentru detectarea aneuploidiilor<\/li>\n<\/ul>\n

        Cultur\u0103 celular\u0103 din lichid amniotic<\/h3>\n
          \n
        • Cariotip clasic (bandare G)<\/strong> pentru analiza complet\u0103 a cromozomilor fetali<\/li>\n
        • Detectarea anomaliilor numerice \u0219i structurale cromozomiale<\/li>\n
        • Interpretare conform ghidurilor interna\u021bionale de genetic\u0103 prenatal\u0103<\/li>\n<\/ul>\n

          Beneficii \u0219i importan\u021b\u0103 clinic\u0103<\/h3>\n
            \n
          • Detectare rapid\u0103 a aneuploidiilor frecvente prin QF-PCR<\/li>\n
          • Evaluare complet\u0103 a cromozomilor prin cariotip<\/li>\n
          • Contribuie la cre\u0219terea acurate\u021bei diagnosticului prenatal invaziv.<\/li>\n
          • Permite decizii medicale rapide \u00een sarcinile cu risc crescut<\/li>\n
          • Identific\u0103 anomalii structurale nedetectate prin screening non-invaziv<\/li>\n
          • Ofer\u0103 suport esen\u021bial pentru consilierea genetic\u0103 prenatal\u0103<\/li>\n
          • Poate reduce incertitudinea \u00een sarcinile cu rezultate modificate la testele de screening.<\/li>\n<\/ul>\n

            Analize asociate recomandate<\/h3>\n

            Pentru evaluare prenatal\u0103 complet\u0103 se recomand\u0103:<\/h3>\n
              \n
            • Test NIPT (ADN fetal liber circulant)<\/strong> \u2013 screening ini\u021bial non-invaziv<\/li>\n<\/ul>\n

              Ecografie morfologic\u0103 fetal\u0103 (trim. I \u0219i II)<\/h3>\n
                \n
              • Array CGH fetal (microarray)<\/strong> \u2013 rezolu\u021bie superioar\u0103 pentru microdelec\u021bii\/microduplica\u021bii<\/li>\n
              • Testare genetic\u0103 parental\u0103 (cariotip)<\/strong> \u2013 \u00een suspiciune de transloca\u021bii ereditare<\/li>\n<\/ul>\n

                Consiliere genetic\u0103 prenatal\u0103 specializat\u0103<\/h3>\n
                  \n
                • Amniocentez\u0103 ghidat\u0103 ecografic<\/strong> \u2013 pentru recoltarea probei<\/li>\n<\/ul>\n

                  Prob\u0103 recoltat\u0103 \/ condi\u021bii analiz\u0103<\/h3>\n
                    \n
                  • Lichid amniotic ob\u021binut prin amniocentez\u0103<\/li>\n<\/ul>\n

                    Volum optim: 15 – 20 ml<\/h3>\n
                      \n
                    • Recoltare \u00een sering\u0103 steril\u0103 non-pirogenic\u0103 (f\u0103r\u0103 man\u0219on de cauciuc)<\/strong><\/li>\n
                    • Transport \u00een condi\u021bii controlate conform protocolului laboratorului<\/li>\n
                    • QF-PCR: rezultat \u00een aproximativ 48 ore<\/strong><\/li>\n
                    • Cariotip din cultur\u0103 celular\u0103: rezultat \u00een 14 – 21 zile lucr\u0103toare<\/strong>,<\/li>\n
                    • Necesit\u0103 condi\u021bii sterile \u0219i efectuare \u00een context obstetrical specializat<\/li>\n<\/ul>\n

                      Denumiri alternative<\/h3>\n
                        \n
                      • Profil genetic prenatal QF-PCR + cariotip<\/li>\n
                      • Cariotip fetal din lichid amniotic<\/li>\n
                      • Analiz\u0103 cromozomial\u0103 prenatal\u0103 complet\u0103<\/li>\n
                      • Amniocentez\u0103 genetic\u0103 (QF-PCR + cariotip)<\/li>\n
                      • Test prenatal invaziv cromozomial<\/li>\n
                      • Analiz\u0103 cromozomi fetali din lichid amniotic<\/li>\n
                      • Prenatal karyotype + QF-PCR testing<\/li>\n
                      • Diagnostic genetic prenatal standard<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

                        Test prenatal invaziv care combin\u0103 QF-PCR rapid<\/strong> \u0219i cariotip din lichid amniotic<\/strong>, utilizat pentru detectarea anomaliilor cromozomiale numerice \u0219i structurale fetale.<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"product_brand":[],"product_cat":[3093,3094],"product_tag":[],"class_list":["post-105463","product","type-product","status-publish","product_cat-pachete","product_cat-pachete-de-analize-medicale","first","instock","sale","shipping-taxable","purchasable","product-type-simple"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t