{"id":16553,"date":"2023-12-11T12:53:33","date_gmt":"2023-12-11T12:53:33","guid":{"rendered":"https:\/\/www.clinica-sante.com\/ro\/?p=16553"},"modified":"2026-03-20T14:46:57","modified_gmt":"2026-03-20T12:46:57","slug":"genotiparea-apoe-apolipoproteina-e","status":"publish","type":"post","link":"https:\/\/www.clinica-sante.com\/ro\/genotiparea-apoe-apolipoproteina-e\/","title":{"rendered":"Genotiparea APOE (Apolipoproteina E)"},"content":{"rendered":"
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Cuprins<\/p>\r\n <\/div>\r\n

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  1. \r\n Ce este APOE?<\/a><\/span>\r\n <\/li>\r\n
  2. \r\n Ce implica\u021bii clinice au aceste genotipuri?<\/a><\/span>\r\n <\/li>\r\n
  3. \r\n Bibliografie<\/a><\/span>\r\n <\/li>\r\n <\/ol>\r\n <\/div>\r\n \r\n\n\n\n
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    \n 1.<\/span>\n Ce este APOE? <\/span> <\/h2>\n<\/div>\n\n\n

    Studiile arat\u0103 c\u0103 APOE este implicat\u0103 \u0219i \u00een procese cognitive \u0219i \u00een reglarea sistemului imun.<\/span>\u00a0<\/span><\/p>\n<\/div>\n\n\n

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    \n \n \n <\/svg>\n <\/div>\n
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    Toate persoanele au aceea\u0219i variant\u0103 APOE?<\/span><\/h2>\n

    Nu! APOE difer\u0103 de la persoan\u0103 la persoan\u0103.\u00a0<\/span>\u00a0<\/span><\/p>\n

    Exist\u0103 3 forme comune ale genei APOE in popula\u021bie: APOE2, APOE3, APOE4 cu diferen\u021be mici de structur\u0103. Aceste diferen\u021be modific\u0103 activitatea proteinei.<\/span>\u00a0<\/span><\/p>\n

    Fiecare persoan\u0103 mo\u0219tene\u0219te 2 gene APOE, c\u00e2te una de la fiecare p\u0103rinte.<\/span>\u00a0<\/span><\/p>\n

    Astfel c\u0103 exist\u0103 6 combina\u021bii posibile, adic\u0103 6 genotipuri diferite pentru APOE:\u00a0<\/span>E2\/E2; E2\/E3; E3\/E3; E3\/E4; E4\/E4; E2\/E4.<\/b>\u00a0<\/span>\ufeff<\/span><\/p>\n<\/p>\n <\/div>\n<\/div>\n\n\n\n

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    \n sus<\/span>\n<\/div>\n\n\n
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    \n 2.<\/span>\n Ce implica\u021bii clinice au aceste genotipuri? <\/span> <\/h2>\n<\/div>\n\n\n